An off-white, homogenous, orange-flavoured oral gel containing miconazole 20 mg/g.
The other ingredients are methylparaben, propylparaben, propylene glycol, potato starch, polysorbate 20, xanthan gum, saccharin sodium, orange flavour and purified water.
DECOZOL oral gel is indicated for the treatment of clinically significant oral and gastrointestinal candidiasis.
Miconazole possesses an antifungal activity against the common dermatophytes and yeasts as well as an antibacterial activity against certain gram-positive bacilli and cocci. Its activity is based on the inhibition of the ergosterol biosynthesis in fungi and the change in the composition of the lipid components in the membrane, resulting in fungal cell necrosis.
For infants 6-24 months, one quarter (1/4) of a measuring spoon of gel four times daily after food, or 20 mg/kg/day is recommended.
Children (2years of age and older) and Adults:
Half (1/2) a measuring spoon of gel four times daily after food.
DECOZOL oral gel should be placed on the tongue and kept in mouth for as long as possible before swallowing. When treating infants and younger children it is recommended that the measured dose of gel be given in several portions in the front of the mouth. Avoid dosing to the back of the throat to prevent obstruction. With oral thrush in elderly patients where a contributing cause is the dental prosthesis it is recommended that DECOZOL oral gel be applied directly to the dentures in the evening and left on overnight. The treatment should be continued for at least one week after the symptoms have disappeared and generally until all clinical and mycological laboratory tests no longer indicate that active fungal infection is present.
DECOZOL Oral Gel is contraindicated in the following situations:
-Substrates known to prolong the QT-interval eg. Astemizole, bepridil,
cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine,
sertindole and terfenadine. Ergot alkaloids.
- HMG-CoA reductase inhibitors such as simvastatin and lovastatin.
-Triazolam and oral midazolam.
If the concomitant use of DECOZOL oral gel and anticoagulants such as warfarin is envisaged, the anticoagulant effect should be carefully monitored and titrated. (see Interactions)
It is advisable to monitor miconazole and phenytoin levels, if they are used concomitantly.
In patients using certain oral hypoglycaemic such as sulfonylureas, an enhanced therapeutic effect leading to hypoglycaemia may occur during concomitant treatment with miconazole and appropriate measures should be considered (see Interactions).
Pregnancy and Lactation
Although there is no evidence that miconazole is embryotoxic or teratogenic in animals, potential hazards of prescribing these medicines during pregnancy should always be weighed against the expected therapeutic benefits.
There are no data available on the excretion of miconazole in human milk; therefore caution should be exercised when breastfeeding women are using DECOZOL.
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Parcels between 1-3kg = $16.95
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Parcels arrive within 3-7 business days.
Express shipped parcels arrive within 1-3 business days (this may be slightly longer for remote country areas).
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Parcels up to 500g = $12.95
Parcels between 0.5-1kg = $24.95
Parcels between 1-1.5kg = $29.95
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